Am J Psychiatry 1980; 137:963-965
Copyright © 1980 by American Psychiatric Association

REGULAR ARTICLES

Treatment of depression in the medically ill elderly with methylphenidate

W Katon and M Raskind

Three depressed geriatric patients had a marked therapeutic response to the psychostimulant drug methylphenidate. These patients either had been unable to tolerate tricyclic antidepressants or had a medical illness that contraindicated tricyclic therapy. The lack of adverse effects in our elderly patients and methylphenidate's effectiveness as an antidepressant were consistent with the findings of other investigators. These results suggest that psychostimulants deserve further evaluation as antidepressant agents in the geriatric population.

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