Am J Psychiatry 1980; 137:1410-1413
Copyright © 1980 by American Psychiatric Association
Poor premorbid adjustment and CT scan abnormalities in chronic schizophrenia
DR Weinberger, E Cannon-Spoor, SG Potkin and RJ Wyatt
The authors evaluated the premorbid adjustment of 51 chronic schizophrenic
patients by retrospective chart analysis using a novel scale. Those
patients with CT evidence suggestive of brain atrophy had significantly
worse premorbid scores, particularly during childhood, than did the
patients with normal scans. This finding provides further support for the
clinical relevance of CT findings in chronic schizophrenic patients and
implicates a neuropathological process that occurs early in development.
