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Am J Psychiatry 1980; 137:1217-1219
Copyright © 1980 by American Psychiatric Association


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Disulfiram encephalopathy as a cause of the catatonia syndrome

WW Weddington Jr, RC Marks and JP Verghese

The authors describe a case of the catatonia syndrome associated with disulfiram therapy. Although useful in the management of chronic alcoholism, disulfiram is being increasingly associated with a wide spectrum of side effects and untoward medical sequelae, which now include catatonia. The authors note that catatonia is a clinical syndrome associated with multiple medical conditions as well as psychiatric disorders.





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