Acute high-dose parenteral haloperidol treatment of psychosis



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Am J Psychiatry 1979; 136:1061-1064
Copyright © 1979 by American Psychiatric Association

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Acute high-dose parenteral haloperidol treatment of psychosis

Y Lerner, E Lwow, A Levitin and RH Belmaker

After 2 days of drug-free observation, 20 newly admitted psychotic patients received 20-35 mg of haloperidol intravenously and 20 patients received 30-40 mg of diazepam intravenously. Posttreatment ratings at 4 and 24 hours with the Brief Psychiatric Rating Scale and the Clinical Global Impressions revealed significant improvement in both groups but no significant differences between the two treatments.

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