Am J Psychiatry 1979; 136:806-810
Copyright © 1979 by American Psychiatric Association
Variable attenuation of amphetamine effects by lithium
B Angrist and S Gershon
In an open study of 8 subjects, approximately half showed some attenuation
of CNS stimulant effects of amphetamine after pretreatment with lithium.
Two showed specific blockade of euphoria, with persistence of some CNS
stimulant effects. In 3 subjects lithium did not appear to affect the
response to amphetamine. Lithium caused significant attenuation of the
amphetamine-induced increase in systolic blood pressure for the group as a
whole.
