Am J Psychiatry 1979; 136:767-771
Copyright © 1979 by American Psychiatric Association
Gonadotropin, estradiol, and testosterone profiles in homosexual men
SR Newmark, LI Rose, R Todd, L Birk and F Naftolin
The authors evaluated the gonadotropin-testosterone-estradiol profiles of
four homosexual men and four heterosexual men by a multiple-sampling
technique. Although there was extensive overlap between the two groups, the
homosexual subjects had higher estradiol levels than the heterosexuals
(70.3 +/- 19.8 versus 56.8 +/- 10.7 pg/ml) and lower FSH values (5.1 +/-
1.0 versus 13.2 +/- 3.4 mIU/ml). Testosterone and luteinizing hormone
levels were comparable in the two groups. These observations suggest that
there may be subtle differences in gonadotropin and estradiol secretion in
homosexual subjects that can be detected only by repeated sampling.
