Am J Psychiatry 1979; 136:1424-1427
Copyright © 1979 by American Psychiatric Association
REM architecture changes in bipolar and unipolar depression
WC Duncan Jr, KD Pettigrew and JC Gillin
The authors compared total night sleep measures and REM sleep architecture
values for normal control subjects (N = 36), unipolar depressed patients (N
= 36), and bipolar depressed patients (N = 22). The unipolar and bipolar
patients had significantly greater fragmentation of REM periods than
control subjects, and bipolar patients showed greater fragmentation of REM
periods than unipolar patients. In both the unipolar and bipolar samples,
the duration of successive REM periods was related to the total number of
REM periods during sleep.
