REM architecture changes in bipolar and unipolar depression



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	Articles by Gillin, J. C.

Am J Psychiatry 1979; 136:1424-1427
Copyright © 1979 by American Psychiatric Association

REGULAR ARTICLES

REM architecture changes in bipolar and unipolar depression

WC Duncan Jr, KD Pettigrew and JC Gillin

The authors compared total night sleep measures and REM sleep architecture values for normal control subjects (N = 36), unipolar depressed patients (N = 36), and bipolar depressed patients (N = 22). The unipolar and bipolar patients had significantly greater fragmentation of REM periods than control subjects, and bipolar patients showed greater fragmentation of REM periods than unipolar patients. In both the unipolar and bipolar samples, the duration of successive REM periods was related to the total number of REM periods during sleep.

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