Am J Psychiatry 1978; 135:1081-1084
Copyright © 1978 by American Psychiatric Association
Phencyclidine-induced psychosis
RM Allen and SJ Young
During a 13-month period, 9 patients with phencyclidine-induced psychosis
were admitted to Darnall Army Hospital. They exhibited hostility agitation,
and tangentiality and had delusions of influence and religious grandiosity.
Six subjects reported auditory hallucinations, and 4 were disoriented in at
least 1 sphere. Despite treatment with antipsychotic medication, the
psychotic episodes often persisted for more than 30 days. Our clinical
finding of prolonged psychotic reactions, together with previous reports of
the effects of phencyclidine, suggests that phenycyclidine provides an
intriguing drug model for schizophrenia.
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