Am J Psychiatry 1978; 135:923-927
Copyright © 1978 by American Psychiatric Association
Impact of neuroleptic chemotherapies on schizophrenic psychoses
P Deniker
The author reviews the impact of neuroleptic chemotherapy on various forms
of schizophrenia in the 25 years since the introduction of chlorpromazine
in psychiatry. The activities of the different types of compounds are
related to the symptomatic and progressive forms of the psychosis, with an
emphasis on the "dual structure" of the illness. Problems of drug efficacy,
the need for new drug treatments, and methodological issues in research in
these areas are discussed.
