Am J Psychiatry 1978; 135:821-825
Copyright © 1978 by American Psychiatric Association
Animal-human correlates of narcotic dependence: a brief review
B Stimmel and SD Glick
Knowledge of opiate action in laboratory animals can be of great value in
developing a rational clinical approach to the treatment of narcotic
dependence. Physiological alterations experimentally produced by narcotics
have been confirmed in human subjects, and classical laboratory effects of
conditioning and operant behavior also have clinical counterparts.
Realization of animal-human correlates of narcotic dependence allows a
better understanding of the strengths and weaknesses of existing
therapeutic modalities.
