Imipramine response in deluded depressive patients



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	Articles by Quitkin, F.
	Articles by Klein, D. F.

Am J Psychiatry 1978; 135:806-811
Copyright © 1978 by American Psychiatric Association

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Imipramine response in deluded depressive patients

F Quitkin, A Rifkin and DF Klein

The authors examined how delusions and other psychotic features influenced treatment outcome with imipramine in patients with primary depression. Global improvement scores indicated that delusions or other evidence of psychosis do not contraindicate imipramine treatment. This finding does not support a recent report suggesting that deluded depressive patients should not be treated with imipramine. Possible explanations of the discrepancy between these two studies are discussed.

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