Am J Psychiatry 1978; 135:333-335
Copyright © 1978 by American Psychiatric Association
Prediction of individual dosage of nortriptyline
TB Cooper and GM Simpson
The authors describe a technique that enables a physician to determine
individual patient dosage requirements for nortriptyline from a single
24-hour blood sample. Because the technique reveals immediately those
patients at the extremes of dosage ranges, toxicity and the need for
time-consuming titration of the dosage regimen can be avoided.