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Am J Psychiatry 1978; 135:333-335
Copyright © 1978 by American Psychiatric Association


REGULAR ARTICLES

Prediction of individual dosage of nortriptyline

TB Cooper and GM Simpson

The authors describe a technique that enables a physician to determine individual patient dosage requirements for nortriptyline from a single 24-hour blood sample. Because the technique reveals immediately those patients at the extremes of dosage ranges, toxicity and the need for time-consuming titration of the dosage regimen can be avoided.


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