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Am J Psychiatry 1977; 134:966-969
Copyright © 1977 by American Psychiatric Association


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Diagnosis: schizophrenia versus posterior aphasia

SN Gerson, F Benson and SH Frazier

Schizophrenia and posterior aphasia are easily cross-diagnosed, primarily because of similarities in verbal output, i.e., vagueness, looseness of association, and apparent confusion. Tape-recorded interviews with 8 posterior aphasics and 10 "loose" schizophrenics were transcribed and analyzed to provide guidelines for the clinician to differentiate the two conditions by monitoring verbal expression. Six major differentiating characteristics were identified. The authors present hypotheses that emphasize differing neuroanatomical loci and neuropsychological mechanisms to explain the differences in verbal output in schizophrenia and posterior aphasia.


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T. E. Goldberg, M. S. Aloia, M. L. Gourovitch, D. Missar, D. Pickar, and D. R. Weinberger
Cognitive Substrates of Thought Disorder, I: The Semantic System
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