Am J Psychiatry 1977; 134:439-440
Copyright © 1977 by American Psychiatric Association
The use of nicotine gum during cessation of smoking
NG Schneider, P Popek, ME Jarvik and ER Gritz
The authors present three case studies which suggest that smoking
withdrawal symptoms in certain individuals may be due to removal of
nicotine per se, implying that smokers may develop a true physical
dependence on cigarettes. Nicotine replacement by use of an experimental
chewing gum containing nicotine in various dosages successfully prevented
or alleviated the abstinence symptoms of the subjects studied.