Am J Psychiatry 1976; 133:814-819
Copyright © 1976 by American Psychiatric Association
l-Alpha-acetylmethadol (LAAM): prognostic considerations
RB Resnick, L Orlin, G Geyer, E Schuyten-Resnick, RS Kestenbaum and AM Freedman
The authors studied the responses of 28 adult male volunteers who were
openly changed from methadone to l-alpha-acetylmethadol (LAAM) maintenance.
They found that patients who had been receiving middle- range doses (50-70
mg) of methadone required a significantly lower mean increase in LAAM than
patients who had been receiving either high or low methadone doses and that
the patients who accepted LAAM differed significantly from those who did
not in MMPI 2-point-code ratings and mean social adjustment scale scores.
These findings may provide prognostic indicators for response to LAAM, a
possible alternative to methadone.
