Am J Psychiatry 1976; 133:444-445
Copyright © 1976 by American Psychiatric Association
Extrapyramidal side effects in lithium maintenance therapy
MH Branchey, J Charles and GM Simpson
The authors neurologically examined 36 patients who had been maintained on
lithium therapy for periods ranging from 6 months to 7 years to determine
the presence of parkinson-like side effects. Only a few patients
demonstrated rigidity, including cogweel rigidity, and this was at a low
level of severity. These results do not support the previously reported
frequent occurrence of cogwheel rigidity in patients on lithium
maintenance.