Am J Psychiatry 1975; 132:641-644
Copyright © 1975 by American Psychiatric Association
Treatment of depression in alcoholics
JA Shaw, P Donley, DW Morgan and JA Robinson
The authors compared two groups of depressed alcoholics given either
placebo or chlordiazepoxide-imipramine in a double-blind study. Although
depression decreased in both groups, there were no significant differences
between them on any of three pre- and posttreament measures. The Zung scale
showed that medication decreased depression significantly, however, this
finding was not supported by the Beck Depression Inventory or by the
Minnesota Multiphasic Personality Inventory, indicating the necessity for
use of multiple assessment instruments.
