Am J Psychiatry 1975; 132:540-542
Copyright © 1975 by American Psychiatric Association
Electrocardiographic monitoring of enuretic children receiving therapeutic doses of imipramine
GI Martin and PJ Zaug
The authors studied the monthly electrocardiographic tracings of 27
children with normal cardiovascular function receiving imipramine therapy
for enuresis. They found no substantial EKG changes in any of these
children, who were receiving doses of 25 to 75 mg of the drug. They
conclude that electrocardiographic monitoring may be essential only when
more than 25 to 75 mg of imipramine is given and that it should be
established that the patient's cardiovascular function is normal before the
drug is administered.