Am J Psychiatry 1975; 132:438-441
Copyright © 1975 by American Psychiatric Association
Platelet monoamine oxidase activity in acute schizophrenia
WT Carpenter Jr, DL Murphy and RJ Wyatt
The authors found normal monoamine oxidase (MAO) activity in 40 acute
schizophrenic patients, in contrast to previous reports of a genetically
linked platelet MAO deficit in chronic schizophrenia. Variations in MAO
activity were not significantly associated with the 65 clinical variables
analyzed, although there was a tendency for patients in the low-MAO group
to have more severely impaired reality testing, more paranoid and grandiose
delusions, better prognostic scores, and less restlessness.
