Tardive and Withdrawal Dyskinesia Associated with Haloperidol
GARY JACOBSON M.D.1,
ROSS J. BALDESSARINI M.D.2, , and
THEO MANSCHRECK M.D.3
1 Assistant Professor, Department of Psychiatry, Massachusetts General Hospital, Eric Lindemann Mental Health Center, and Harvard Medical School, Boston, Mass.
2 Associate Professor, Department of Psychiatry, Massachusetts General Hospital, Eric Lindemann Mental Health Center, and Harvard Medical School, Boston, Mass.
3 Resident, Department of Psychiatry, Massachusetts General Hospital, Eric Lindemann Mental Health Center, and Harvard Medical School, Boston, Mass.
Four cases of dyskinesia attributable to treatment with 4-20 mg. of haloperidol daily for more than a year are reported. Two cases involved temporary oral-facial dyskinesias and the others a more persistent complex mixture of neurological features. The possibility that tardive dyskinesia may be associated with the butyrophenones in addition to other antipsychotic agents should be considered, the authors believe.
