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Am J Psychiatry 131:682-687, June 1974
doi: 10.1176/appi.ajp.131.6.682
© 1974 American Psychiatric Association
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Cross-Cultural Evaluation of Schneider’s First-Rank Symptoms of Schizophrenia: A Report from the International Pilot Study of Schizophrenia

WILLIAM T. CARPENTER JR. M.D.1, and JOHN S. STRAUSS M. D.2

1 Acting Chief, Psychiatric Assessment Section, Adult Psychiatry Branch, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, Md. 20014
2 Director, Clinical Psychiatry Research Programs, University of Rochester School of Medicine and Dentistry, Rochester, N.Y.

The authors analyzed diagnostic data collected in nine countries in an effort to determine the clinical usefulness of Kurt Schneider's II "first-rank symptoms" (FRSs) of schizophrenia. The study specifically sought to determine whether the prevalence of FRSs in patients diagnosed as schizophrenic (N = 811) justified their use in diagnosis, what the frequency distribution was among FRSs, and whether or not FRSs were pathognomonic of schizophrenia, as Schneider claimed. The findings showed that FRSs do occur with sufficient frequency to have potential diagnostic usefulness and that each of the nine FRSs analyzed is highly discriminating for schizophrenia. However, since FRSs were also reported in patients receiving other psychiatric diagnoses. FRSs cannot be considered absolutely discriminating for schizophrenia.




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