Mesoridazine Versus Chlorpromazine in Acute Schizophrenia: A Double-Blind Investigation
T. A. HAMID M.D.1, and
WILLIAM J. WERTZ M.D.2
1 16 Nile St., Giza, Egypt, U.A.R.
2 Superintendent, Detroit Psychiatric Institute, 1151 Taylor St., Detroit, Mich. 48202
A double-blind comparison of mesoridazine and chlorpromazine with 91 newly admitted, acutely psychotic patients showed that symptoms grouped in the following composites improved significantly more in the mesoridazine patients than in the chlorpromazine patients: motor activity, attitude and behavior, emotional response, and ideation and thought processes. The mesoridazine patients experienced less sedation than the chlorpromazine patients.
