The 24-Hour Serum Lithium Level as a Prognosticator of Dosage Requirements
THOMAS B. COOPER M.A.1,
PER-ERICK E. BERGNER M.SC., M.D.1, , and
GEORGE M. SIMPSON M.D.2
1 Chief Investigators, Research Center, Rockland State Hospital, Orangeburg, N.Y. 10962
2 Principal Research Psychiatrist, Research Center, Rockland State Hospital, Orangeburg, N.Y. 10962
A technique is described that enables a physician to determine a patient's lithium dosage requirement on the basis of a single blood sample collected 24 hours after the administration of a 600 mg. priming dose of lithium. The authors discuss the basis of this technique and emphasize the importance of ascertaining that the patient has ingested the priming dose of lithium.