Imipramine Withdrawal: An Akathisia-Like Syndrome
GREGORY L. SATHANANTHAN M.D., D.P.M.1, and
SAMUEL GERSHON M.D., D.P.M.2
1 Clinical Instructor of Psychiatry, Neuropsychopharmacology Research Unit, Department of Psychiatry, New York University Medical Center, 550 First Ave., New York, N.Y. 10016
2 Professor of Psychiatry, Neuropsychopharmacology Research Unit, Department of Psychiatry, New York University Medical Center, 550 First Ave., New York, N.Y. 10016
The authors report on three patients who developed an akathisia-like syndrome after the abrupt withdrawal of imipramine. They discuss a possible link between this phenomenon and dopamine turnover in the central nervous system.
