Single Versus Divided Daily Dose of Trimipramine in the Treatment of Depressive Illness
M. Z. HUSSAIN D.P.M.1, and
Z. A. CHAUDHRY M.B.2
1 Senior Psychiatrist, Psychiatric Centre, Victoria Union Hospital, 1200-24th St. West, Prince Albert, Sask., Canada
2 Resident in psychiatry, Psychiatric Centre, Victoria Union Hospital, 1200-24th St. West, Prince Albert, Sask., Canada
A group of 56 patients with depressive illnesses were administered either a single daily dose or a divided daily dose of trimipramine on a random basis. Results of the treatment showed several advantages for the use of a single daily dose: a trend toward better therapeutic improvement, a significant decrease in the side effects of insomnia and fatigue, and more regular consumption of the medication.
