Persistence of Neurological Symptoms Due to Neuroleptic Drugs
GEORGE E. CRANE M.D.1
1 Director of Medical Research, Spring Grove State Hospital, Baltimore, Md. 21228
The author examines the problem of extrapyramidal symptoms attributable to neuroleptic drugs. Thirty-nine patients with tardive dyskinesia and/or pseudoparkinsonism did not receive neuroleptics for six to 24 months. At the end of this time, 36 patients manifested symptoms consistent with tardive dyskinesia. In five of 12 patients who had pseudoparkinsonism, alone or with tardive dyskinesia, parkinsonian symptoms persisted for six months or longer.
