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Am J Psychiatry 125:544-548, October 1968
doi: 10.1176/appi.ajp.125.4.544
© 1968 American Psychiatric Association
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Recurrent Depressions and the Lithium Ion

WILLIAM L. DYSON M.D.1, and MYER MENDELSON M.D.2

1 Departments of psychiatry and surgery, University of Pennsylvania School of Medicine, Philadelphia, Pa. 19104
2 Department of psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pa. 19104

Lithium was successfully used to treat five patients with recurrent depressions, three of whom had typical manic-depressive illnesses. Their clinical and also their characteristic subjective responses to lithium establish a very suggestive relationship between illnesses previously believed on observational grounds alone to be related. Some term such as "lithium-responders" might appropriately delineate this group of patients.







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