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Am J Psychiatry 124:1585-1588, May 1968
doi: 10.1176/appi.ajp.124.11.1585
© 1968 American Psychiatric Association
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A Study of the Withdrawal of Chlorpromazine or Trifluoperazine in Chronic Schizophrenia

M. R. MORTON M.B., D.P.M.1

1 Senior psychiatric registrar, John Conolly Hospital, Bristol Road South, Rednal, Birmingham, England

Because the importance of tranquilizing drugs has been difficult to assess precisely, the author undertook a study on the effect of the withdrawal of chlorpromazine and trifluoperazine on hospitalized male schizophrenics in England. Although there were no major relapses among the placebo group, changes occurred that were sometimes disabling.







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