A Double-Blind Study of the Effect of Ribonucleic Acid in Senile Brain Disease
JOHN H. NODINE M.D.1,
MARK W. SHULKIN M.D.2,
JOSEPH W. SLAP M.D.3,
MURRAY LEVINE PH.D., , and
KENNETH FREIBERG 4
1 Associate Professor of Medicine, Section of Clinical Pharmacology
2 Senior Instructor, Department of Psychiatry
3 Clinical Assistant Professor of Medicine and Psychiatry
4 Assistant Professor of Psychology, Yale University, New Haven, Conn.
A double-blind study to test the effect of orally administered ribonucleic acid upon the course of senile and arteriosclerotic brain disease failed to confirm the positive findings of other investigators. The authors conclude that RNA administered in this form does not appear to bring about improvement or reversal of senile brain disease.
