VISUAL HALLUCINATIONS WITH IMIPRAMINE
DONALD F. KLEIN M.D.1
1 Senior Staff Psychiatrist, Research Department, Hillside Hospital, Glen Oaks, N. Y.
The occasional occurrence of imipramine-induced visual hallucinations resembling those produced by hallucinogenic agents is documented. The phenomenon is dosage dependent and easily managed by reduction of dosage level when recognized. Delirious confusion is not a necessary part of this syndrome. This phenomenon's relationships to age, diagnosis, and psychopathological features are discussed and contrasted with visual hallucinations of schizophrenia. The possibility of a common organic CNS predisposition to depersonalization, derealization, and visual hallucinosis is indicated.
