TRANSIENT TOXICITY WITH CARPHENAZINE HYDROCHLORIDE
J. MENDELS M.B.CH.B.1
1 Registrar in Neuro-Psychiatry, Tara Hosptial for Nervous and Mental Diseases and University of the Witwatersrand, P.O. Box 13, Saxonwold, Johannesburg, South Africa
Four patients who developed signs of hepatic and haematological toxicity while being treated with carphenazine hydrochloride are reported. The drug was stopped in one patient and continued in 3. All signs of toxicity disappeared in 12-16 weeks, without any reduction in dosage.
