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Am J Psychiatry 120:878-881, March 1964
doi: 10.1176/appi.ajp.120.9.878
© 1964 American Psychiatric Association
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THE PROGNOSIS IN "ORGANIC BRAIN" SYNDROMES

SAMUEL B. GUZE M.D.1, and DENNIS P. CANTWELL B.S.

1 Associate Professor of Psychiatry, Washington University School of Medicine, St. Louis, Mo.

A study of 117 patients with "organic brain" syndrome seen in consultation over a 4-year period indicated that this syndrome is associated with a poor prognosis. A high mortality rate, frequent subsequent psychiatric hospitalization, and frequent dementia were noted on follow-up. Significant anatomical and chemical abnormalities were found in most of those who died and were autopsied to provide an explanation for the psychiatric illness.







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