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Am J Psychiatry 120:595-597, December 1963
doi: 10.1176/appi.ajp.120.6.595
© 1963 American Psychiatric Association
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THORAZINE AS AN EPILEPTOGENIC AGENT

WILLIAM S. MCCABE M.D.1, and JOSEPH A. HABOVICK R.N.2

1 Staff Psychiatrist, Woodville State Hospital, Woodville, Pa.
2 Staff Nurse, Woodville State Hospital, Woodville, Pa.

Thorazine is not an epileptogenic agent, instead it acts synergistically with Dilantin and Mysoline to reduce both the number and severity of grand mal seizures. An incidental finding was that Dilantin significantly alters the behavior of a number of schizophrenics when added to their daily medication indicating a stimulation of schizophrenic-like behavior in a certain number of sub-threshold (sub-clinical) convulsive individuals.







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