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Am J Psychiatry 120:186-187, August 1963
doi: 10.1176/appi.ajp.120.2.186
© 1963 American Psychiatric Association
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AN UNUSUAL REACTION TO COMBINED IMIPRAMINE-THORAZINE THERAPY

FRANCIS J. KANE JR. M.D.1, and T. W. TAYLOR M.D.2

1 Univ. of North Carolina, Chapel Hill, N. C.
2 North Carolina Memorial Hospital, Chapel Hill, N. C.

An unusual syndrome with impairment of speech, generalized tremor, hyperactive DTR's, persistent clonus, and equivocal Babinski reflexes is reported with combined imipramine-thorazine therapy.







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