PERPHENAZINE AND AMITRIPTYLINE AS ADJUNCTS TO PSYCHOTHERAPY

doi:10.1176/appi.ajp.120.1.76

Am J Psychiatry 120:76-77, July 1963
doi: 10.1176/appi.ajp.120.1.76
© 1963 American Psychiatric Association



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	Articles by SMITH, M. E.

PERPHENAZINE AND AMITRIPTYLINE AS ADJUNCTS TO PSYCHOTHERAPY

MARSHALL E. SMITH M.D.

Combinations of 2 or 4 mg. perphenazine and 10 or 25 mg. amitriptylinewere used as adjuncts to psychotherapy in 65 outpatients. Theeffect of the chemotherapy was considered excellent in 2 patients,good in 32, fair in 14, and none in 17. This agent appears tobe most useful in agitated depression and least useful in schizophrenia.The major side effect was dryness of the mouth.

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