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Am J Psychiatry 119:427-431, November 1962
doi: 10.1176/appi.ajp.119.5.427
© 1962 American Psychiatric Association
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IMIPRAMINE IN DEPRESSION : A CONTROLLED STUDY

NORMAN ROULET M.D., ROBERT R. ALVAREZ PH.D., J. PATRICK DUFFY M.D., L. DOUGLAS LENKOSKI M.D., , and T. GEORGE BIDDER M.D.1

1 University Hospitals of Cleveland and the Dept. of Psychiatry, Western Reserve University School of Medicine.

The antidepressant drug imipramine was evaluated by means of a double blind study. Therapeutic results were assessed on the basis of a rating scale, psychological tests, and clinical course. Differences favoring the drug were found in some of the psychological tests, but in no clinical area were there significant differences between drug and placebo.







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