HIGH DOSAGES OF MEPROBAMATE IN CHRONIC SCHIZOPHRENIA
LAURENCE H. SNOW M.D.1,
KARL RICKELS M.D.2, , and
HAROLD H. MORRIS M.D.3
1 Instructor, Dept. of Psychiatry, University of Pennsylvania.
2 Assistant Professor, Dept. of Psychiatry, University of Pennsylvania.
3 Associate Professor, Dept. of Psychiatry, University of Pennsylvania.
1. Meprobamate in high dosage seems to be of value in the treatment of some chronic schizophrenic patients. If it is, it will exert its clinical effects in a relatively short time.
2. High dosage meprobamate seems efficacious in the facilitation of abreactive recall, even when the drug alone is not sufficient to bring about a clinical change.
3. The absence of side-effects other than transient somnolence makes meprobamate a relatively easy drug to use in a controlled inpatient setting.
4. Further studies seem indicated to evaluate adequately large dosage meprobamate therapy in schizophrenia.
