A TOXIC REACTION TO COMBINED ELAVIL-LIBRIUM THERAPY
FRANCIS J. KANE JR. M.D., and
TERRY W. TAYLOR M.D.1
1 University of North Carolina, Dept. of Psychiatry, Chapel Hill, N. C.
The occurrence of an acute brain syndrome with evidence of cerebellar dysfunction following the ingestion of Librium and Elavil concomitantly would seem to indicate an enhancement of the toxic effect of these drugs and would indicate extreme caution in their use together. The occurrence of similar incompatibilities among drugs used and the treatment of depression is well known and fatalities have been reported.
