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Am J Psychiatry 118:249-250, September 1961
doi: 10.1176/appi.ajp.118.3.249
© 1961 American Psychiatric Association
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A METHOD FOR SERIAL SAMPLING OF BLOOD DURING SLEEP

JAMES L. MATHIS M.D.1, BOYD K. LESTER M.D.2, , and CHESTER M. PIERCE M.D.2

1 Resident in psychiatry, University of Oklahoma School of Medicine, Oklahoma City, Okla.
2 Assistant professor of psychiatry, University of Oklahoma School of Medicine, Oklahoma City, Okla.

An indwelling polyethylene tube in a large superficial vein offers a simple, safe, economical technique for obtaining serial blood samples without disturbing a sleeping subject. This permits study of hematological correlates of depth of sleep, diurnal and other periodic changes, and episodes of dreaming.







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