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Am J Psychiatry 117:457-458, November 1960
doi: 10.1176/appi.ajp.117.5.457
© 1960 American Psychiatric Association
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THE USE OF FLUPHENAZINE (PROLIXIN) IN REHABILITATION OF CHRONIC SCHZOPHRENIC PATIENTS

LEON REZNIKOFF M.D.1

1 Clinical Director, Hudson County Hospital for Mental Diseases, Secaucus, N. J.

1. Fifty chronic schizophrenic patients with an average duration of mental illness of over 12 years and refractory to any other treatment had been treated with fluphenazine for a period of 3 to 4 months.

2. Twenty-nine patients (58%) improved and 21 (42%) remained unimproved.

3. The dose of fluphenazine varied from 2.5 mg. to 20 mg. per day. When the dose of fluphenazine was raised over 10 mg. per day, 50% of patients developed extrapyramidal symptoms.

4. Fluphenazine is a valuable adjunct in the total program of rehabilitation of chronic schizophrenic patients.







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