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Am J Psychiatry 117:157-159, August 1960
doi: 10.1176/appi.ajp.117.2.157
© 1960 American Psychiatric Association
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PRELIMINARY RESULTS WITH FLUPHENAZINE (PROLIXIN) IN CHRONIC PSYCHOTIC PATIENTS

JOHN P. HOLT M.D., and ELEANORE R. WRIGHT M.D.1

1 Embreeville State Hospital, Embreeville, Pa.

Fluphenazine is a highly potent psychopharmacologic agent which is effective in controlling behavioral symptoms in chronic psychotic patients with the most pronounced changes manifested in reduced agitation and tension and improved socialization; the drug is also effective in controlling hallucinations and delusions. Through greater individualization of dosage may be required with fluphenazine than with other phenothiazines for maximum benefit with minimum reactions, fluphenazine appears to have great potential usefulness in the treatment of chronic psychotic patients.







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