TOXIC AND OTHER SIDE EFFECTS OF NARDIL PHENELZINE SULPHATE W-1544A
UJAMLAL C. KOTHARI M.D.1
1 Danville State Hospital, Danville, Pa.
This article being mainly about the side effects of phenelzine sulphate, its value as an anti-depressant agent is not discussed.
Risk of hepatotoxic effects of this drug is worth keeping in mind as 7 out of 13 cases showed some abnormality of liver function test. Phenelzine sulphate may produce drug rash as many other drugs do. Patients, having low or fluctuating blood pressure may develop hypotensive reaction while on this drug and should be under close supervision. Sometimes it produces side effects like insomnia and restlessness which can be relieved by sedative and Meprobamate.
No toxic effects on kidneys or blood were observed in our study.
All the above effects are mild and reversible and may he treated by reducing or discontinuing the medication and with adjuvant therapy.
