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Am J Psychiatry 116:365-367, October 1959
doi: 10.1176/appi.ajp.116.4.365
© 1959 American Psychiatric Association
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SCHIZOPHRENIA ASSOCIATED WITH ADDISON'S DISEASE

HAROLD D. WOLFF M.D., and P. E. HUSTON M.D.1

1 Department of Psychiatry, College of Medicine, State University of Iowa, Iowa City, Iowa.

A patient is presented who showed an acute schizophrenic reaction. Treated with ECT, there was marked improvement. Four weeks later the schizophrenic symptoms returned accompanied by signs and symptoms of Addison's disease. Treated with hormones, there was a remission of both the Addison's disease and the mental symptoms.

After one year of maintenance on cortisone, the patient is without evidence of schizophrenia or Addison's disease.




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The Neuropsychiatric Profile of Addison's Disease: Revisiting a Forgotten Phenomenon
J Neuropsychiatry Clin Neurosci, November 1, 2006; 18(4): 450 - 459.
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