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Am J Psychiatry 115:452-454, November 1958
doi: 10.1176/appi.ajp.115.5.452
© 1958 American Psychiatric Association
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TRILAFON IN THE TREATMENT OF CHRONICALLY PSYCHOTIC HOSPITALFZED PATIENTS

HARRY COHEN M. D.1, and ANNA Z. FREIREICH M. D.2

1 Supervising Psychiatrist, Brooklyn State Hospital, Brooklyn, N. Y.
2 Senior Psychiatrist, Brooklyn State Hospital, Brooklyn, N. Y.

1. Experience with a new " tranquilizer", Trilafon or perphenazine, in treating 90 chronically psychotic hospitalized female patients for a limited period is described.

2. The effects were noted during the period of active administration of the drug and then for a period after termination of the drug therapy. Seventy-two percent of the patients showed some degree of improvement; 15% rose above minimal clinical gains.

3. Side-effects were not serious, were controllable and no deterrent to therapy. The absence of jaundice, blood-dyscrasia and photo-sensitivity are noteworthy.

4. The overall impression is that Trilafon is a useful drug with possibly distinct advantages over the older " tranquilizers" in the treatment of chronically psychotic hospitalized patients.







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