A RAPID URINE COLOR TEST FOR TRIFLUPROMAZINE (VESPRIN)
FRED M. FORREST M.D.1,
IRENE S. FORREST PH.D.2, , and
AARON S. MASON M.D.3
1 Chief, Acute Service, VA Hospital, Brockton, Mass.
2 Research Biochemist, VA Hospital, Brockton, Mass.
3 Director, Professional Services, VA Hospital, Brockton, Mass.
A specific urinary color test for triflupromazine (Vesprin) is reported in which 1 ml. of urine is mixed with 1 ml. 10% trichloracetic acid. To this mixture 1 ml. of 1/1000 molar solution of uranyl nitrate in concentrated hydrochloric acid is added. The resulting color is read within 30 seconds against a color chart showing three color intensities, marked +, ++ and +++, for daily drug doses ranging from 10 to 600 mg. of drug. No false negatives were encountered, and 0.6% false positive tests were seen. Potential factors of interference are discussed.
