CLINICAL NOTES
HYALURONIDASE IN THE TREATMENT OF LOCAL INFLAMMATORY EFFECTS FOLLOWING INTRAVENOUS INJECTION OF 50% GLUCOSE
JOSEPH PETRUS M. D.1, and
JOSEPH PISETSKY M. D.1
1 The Neuropsychiatric Service of the Veterans Administration Hospital, Bronx, N. Y.
Although the number of cases is admittedly small, the results seem to indicate that 0.5 cc. of hyaluronidase solution, containing 150 TR units per cc., when injected subcutaneously into any area of pain and swelling following intravenous injection of 50% glucose, is sufficient to reduce the usual 1-or 2-week course of the condition to 1 or 2 days.
This treatment also seems to prevent the development of such complications as progressive cellulitis, lymphangitis, and thrombophlebitis in such areas.
For best results, the hyaluronidase should be injected as soon as possible after the development of the swelling, but delayed treatment, for as much as 48 hours, still seems to have some benefit.
