THE USE OF U 500 INSULIN IN DEEP INSULIN COMA
G. DONALD NISWANDER M. D.1, and
MURIEL C. NELSON R. N.1
1 The Department of Psychiatry, Harvard Medical School and the Boston Psychopathic Hospital.
U 500 insulin did not induce therapeutic comas more readily than other conventional concentrations of insulin. The time required for the development of the therapeutic coma was not altered by the use of U 500. Delayed insulin reactions were not more frequent with U 500 insulin than with other types provided the total dosage was equivalent. No untoward clinical effects were noted when U 500 was employed. U 500 insulin can be recommended for deep insulin coma in the treatment of mentally ill patients.
