A METHOD OF EVALUATING A THERAPEUTIC AGENT
Results in a Study of Dibenamine
ALBERT J. STUNKARD M. D.1
1 The Henry Phipps Psychiatric Clinic, The Johns Hopkins Hospital.
1. A method of evaluating a therapeutic agent in psychiatric disorders is described. [see Tabel 1 in source pdf]
2. Advantages and disadvantages of such a method are discussed.
3. This method is used in a study of the effects of dibenamine in 30 patients suffering from various psychiatric disorders.
4. It is demonstrated that in the dosage used dibenamine is not more effective than a placebo in the care of patients as described.
5. Nausea and vomiting occurred in 11 of 30 patients receiving dibenamine, as against 2 receiving placebo.
6. An increase of symptoms was found in 3 of 5 depressed patients receiving dibenamine.
