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Am J Psychiatry 104:280-281, October 1947
doi: 10.1176/appi.ajp.104.4.280
© 1947 American Psychiatric Association
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CASE REPORT

SUCCESSFUL TREATMENT OF A CASE OF PHENOBARBITAL POISONING WITH PICROTOXIN

SAMUEL LIEBMAN M. S., M. D., and L. WAYNE JOHNSON B. S., B. M.

A case of phenobarbital poisoning in a chronic alcoholic is reported, in which the patient is believed to have taken about 10 grams of phenobarbital and was comatose for 109 hours and lethargic for 149 hours. She received a total of 2,526 mgms. of picrotoxin. We believe this is the largest reported dose of picrotoxin used in barbiturate poisoning with recovery of the patient.






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