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Predictors of interepisode symptoms and relapse in affective disorder patients treated with lithium carbonate

Published Online:https://doi.org/10.1176/ajp.144.3.367

For 98 affective disorder patients receiving lithium prophylaxis for a mean of 45 months, number of interepisode symptoms correlated with relapse rate. Response to prophylaxis appeared highly determined by prelithium frequency of episodes and duration of lithium treatment.

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